Join Dr. Chris Magryta and Dr. Erik Lundquist for a clinically rigorous 6-week intensive focused on advanced lab interpretation for complex patient care. This course explores emerging biomarkers that illuminate early dysfunction across cardiovascular, metabolic, immune, and endocrine systems long before conventional diagnostic thresholds are crossed.

Live calls with Dr. Chris Magryta and Dr. Erik Lundquist will be held at 4 PM PST / 7 PM EST on Wednesday, October 29th, November 5th, 12th, & 19th, December 3rd and 10th.

All live sessions are 60 minutes, recorded, and accessible to enrolled students.

What you'll learn:

This advanced educational course offers a systems-biology framework for interpreting emerging laboratory markers. Designed for healthcare professionals, it explores the evolving landscape of clinical biomarkers and their potential roles in assessing physiological patterns across interconnected domains such as oxidative stress, immune signaling, metabolic activity, and endocrine balance.

Through case-based discussions, you’ll examine the scientific rationale behind various biomarkers, including Lp-PLA2, OxLDL, F2-Isoprostanes, methylation intermediates, cytokine profiles, antibody subclasses, and adrenal-related indicators and explore how they may reflect broader biological dynamics.

This course emphasizes pattern recognition over isolated analysis, encouraging participants to integrate laboratory data within a broader context of systems physiology. Discussions focus on interpreting biomarker trends as part of a comprehensive clinical picture, with an emphasis on emerging research and investigational insights.

By the end of the course, participants will be able to recognize patterns among advanced biomarkers and understand their proposed physiological relevance. They will explore how laboratory data may inform functional hypotheses related to patient presentations and apply systems-thinking strategies to lab interpretation within the context of integrative and personalized care models.

Course outline:

• Week 1: Cardiovascular Physiology
  Examine the scientific context of markers such as Lipoprotein(a), OxLDL, myeloperoxidase, and F2-Isoprostanes. Explore how these biomarkers are studied in relation to lipid metabolism, oxidative stress, and genetic factors.
• Week 2: Metabolic Dynamics
  Review research on metabolic markers such as adiponectin, leptin, 8OHdg, and fatty acid ratios. Discuss how these may be evaluated as part of broader nutritional and metabolic assessments.

• Week 3: Nutrient and Cofactor Status
  Explore the relevance of B vitamins, glutathione, vitamin C, and related metabolites in cellular processes. Analyze how these markers are used in research on antioxidant capacity and one-carbon metabolism.

•  Week 4: Immune Signaling and Balance
  Gain insight into the scientific interpretation of cytokines, T-cell profiles, and NK cell activity. Discuss how immune signaling is studied in relation to systemic inflammation and immune system modulation.

• Week 5: Immunoglobulin and Antibody Patterns
  Understand the theoretical models of immune dysregulation and autoantibody production. Learn to evaluate immunoglobulin panels and subclass distributions in a non-diagnostic, exploratory framework.

• Week 6: Endocrine and Neuroendocrine Integration
  Investigate how thyroid, adrenal, and sex hormone markers may interact with immune and metabolic indicators. Consider emerging research on circadian biology, stress response, and resilience.